Background:

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA.

Applications:

WB

Name of antibody:

MBD3

Immunogen:

Synthesized peptide derived from C-terminal of human MBD3.

Full name:

methyl-CpG binding domain protein 3

Synonyms：

0

SwissProt:

O95983

WB Predicted band size:

33 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000