Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.

Applications:

ELISA, IHC

Name of antibody:

MCM7

Immunogen:

Fusion protein of human MCM7

Full name:

minichromosome maintenance complex component 7

Synonyms：

MCM2; CDC47; P85MCM; P1CDC47; PNAS146; P1.1-MCM3

SwissProt:

P33993

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human cervical cancer

IHC Recommend dilution:

25-100